October 15, 2017 Sunday
6:00 pm - 8:00 pm Welcome Reception & Registration
October 16, 2017 Monday
8:00 am - 8:45 am Registration, Coffee & Tea
8:45 am - 9:00 am Welcome
9:00 am - 9:40 am Keynote Lecture
Dr. Richard M. Caprioli
Professor of Biochemistry
Director of the Mass Spectrometry Research Center
Vanderbilt University School of Medicine
9:40 am - 10:00 am Break
10:00 am - 12:00 pm Drug Discovery and Development
Chair: Dr. Reid Groseclose, Fellow/Senior Investigator, GSK
"Mass Spectrometry Imaging in Drug Research And Development" - Per Andrén, Uppsala University, Sweden
"Applying MALDI Imaging Mass Spectrometry to Dermal Studies: Assessment of Penetration Depth" - Jeremy Barry, GSK, King of Prussia, PA
"Label-Free Imaging and Quantification of Therapeutic Peptides and Metabolites in Tissues" - Marissa Vavrek, Merck, West Point, PA
"Mass Spectrometry Imaging Applications to Drug Development and Efficacy" - Erin Seeley, Protea Biosciences, Morgantown, WV
"Where is my drug and What is it doing? Validating Drug Delivery and Investigating Endogenous changes" - William Hardesty, GSK, King of Prussia, PA
"Intra-Tumor PK/PD Evaluation by Quantitative Mass Spectrometry Imaging in Immuno-Oncology" - David Calligaris, Imabiotech, Billerica, MA
12:00 pm - 12:15 pm Attendee Group Photo
12:15 pm - 1:30 pm Lunch
1:30 pm - 2:00 pm What's New!
Moderator: Dr. Peggi Angel
“What’s new with Bruker Imaging” - Dr. Shannon Cornette, Global MS Imaging Market Manager, Bruker
“New HTX sample preparation platforms for molecular imaging. HTX M5 Sprayer and SepQuant dropletProbe Liquid Interface to HPLC/MS” - Alain Creissen, Imaging Product Manager, HTX Imaging
2:00 pm - 4:30 pm New Methods and Applications
Chair: Dr. Pierre Chaurand, Full Professor, Université de Montréal
“Understanding the laser desorption ionization mechanisms of lipids from tissue sections after matrix deposition by sublimation” - Pierre Chaurand, Université de Montréal,
"New Approaches for Multimodal Ambient Imaging of Biological Samples" - Julia Laskin, Purdue University, Lafayette IN.
"Metabolomic and chemical labeling approaches to extend N-glycan detection by MS imaging" - Richard Drake, MUSC, Charleston SC.
“Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI FT-ICR” - Peggi Angel, MUSC, Charleston SC.
“Imaging Mass Spectrometry of Ocular Tissues: Unique Challenges and Opportunities” - Kevin Schey, Vanderbilt University, Nashville, TN.
“Imaging mass spectrometry of blood traces in fingermarks” - Nidia Lauzon, Université de Montréal.
4:30 pm - 6:00 pm Poster
6:00 pm - 7:00 pm Cocktail
7:00 pm - 9:00 pm Dinner
October 17, 2017 Tuesday
8:00 am - 9:00 am Coffee & Tea
9:00 am - 11:30 am Instrumentation
Chair: Dr. Jeffrey Spraggins, Research Assistant Professor, Vanderbilt University
“Emerging Molecular Imaging Technologies by Matrix-Free Nanophotonic Ionization and Ultrahigh Resolution LAESI-21T-FTICR” - Sylwia Stopka, George Washington University, Washington DC
“Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) for Mass Spectrometry Imaging: Source Design and Innovations” - Mark Bokhart, North Carolina State University, Raleigh, NC
“Multi-platform imaging mass spectrometry reveals novel insights into kidney disease” - Nichole Lareau, Vanderbilt University, Nashville, TN
“Increased confidence in both molecular identification and localization using multimodal MSI in conjunction with spatially resolved MS²“ - Chris Anderton, Pacific Northwest National Laboratory, Richland, WA
“SolariX 2xR: Enabling routine isotopic fine structure and other benefits for imaging” - Shannon Cornett, Bruker Daltonics, Billerica MA
“Thin Tissue Surface Profiling using Droplet-Based Liquid Microjunction Surface Sampling Mass Spectrometry” - Vilmo Kertesz, Oak Ridge National Laboratory, Oak Ridge, TN
11:30 am - 1:00 pm Lunch
1:00 pm - 1:40 pm What’s New!
Moderator: Dr. Peggi Angel
“ImaBiotech New Facility, New Services” - Jonathan Stauber, Founder & CEO ImaBiotech, ImaBiotech
“Liquid Extraction Surface Analysis Mass Spectrometry (LESA-MS): Examples of spatially resolved information from biological samples” - Dr. Daniel Eikel, Product Manager, Advion Inc.
"What's new in DESI and multimodal imaging mass spectrometry?" – Roy Martin, Sr. Manager Biological Mass Spectrometry, Waters.
1:40 pm - 3:40 pm Data Analysis and Quantitation
Chairs: Dr. Olga Vitek, Sy and Laurie Sternberg Interdisciplinary Associate Professor, Northeastern University and
Dr. Kylie Bemis, Postdoctoral Future Faculty Fellow, Northeastern University
“MSI based molecular histology: looking beyond morphology” - Liam McDonnell, Leiden University Medical Center, the Netherlands.
“Current status and future perspectives of the open data format imzML” - Andreas Römpp, University of Bayreuth, Bayreuth, Germany.
“MSiReader: Open-Source Software for Visualization and Analysis of MSI Data” - Kenneth P. Garrard, North Carolina State University, Raleigh, NC.
“Analyzing OpenMSI datasets with Jupyter notebooks” - Benjamin Bowen, Lawrence Berkeley National Lab, CA.
“Scaling open-source workflows for larger-than-memory MSI experiments” - Kylie Bemis, Northeastern University, Boston MA.
“Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs” - April Harry, Purdue University, West Lafayette, IN; Northeastern University, Boston, MA.
3:40 pm - 5:40 pm Poster
October 18, 2017 Wednesday
8:30 am - 9:00 am Coffee & Tea
9:00 am - 9:20 am Jan Kobarg, SCiLS, Bremen, Germany: TBD
9:20 am - 10:10 am Open Forum I: “IMS and the Pharmaceutical Industry Perspective” Dr. Steve Castellino, Chair:
10:10 am - 11:00 am Open Forum II: “IMS Challenges & Opportunities” Dr. Kevin Schey, Chair
11:00 am - 11:15 am Closing Remarks