2 pre-meeting workshops will take place on Saturday, July 30th in the Elm Ballroom at the SMC Campus Center.
Pre-Meeting Workshop 1: MSiReader Pro: An Intuitive and Innovative Vendor Neutral Software for Mass Spectrometry Imaging
Saturday, July 30th - 1:00pm-3:00pm
Current software solutions for analyzing mass spectrometry imaging (MSI) data are either cost-prohibitive and vendor-specific, i.e., optimized for proprietary data formats, and/or lack diverse functionality, ease-of-use, documentation, and technical support. This workshop will cover basic functions within MSiReader Pro as well as several advanced functions; MSiReader Pro is vendor-neutral and a user-centric solution providing a diverse array of advanced tools. MSiReader Pro reader enables researchers to turn raw MSI data into biological insights, helping accelerate biomedical innovations that positively affect human health. Sufficient time will be dedicated to discussion so we can answer specific questions and discuss future algorithms or changes to better support the MSI community.
Pre-Meeting Workshop 2: Strategic Design of MALDI Imaging Sample Preparation
Saturday, July 30th - 3:00pm-4:00pm
This workshop is designed for scientists who want to learn and refine techniques for strategic design of MALDI imaging sample preparation, with an emphasis on high spatial resolution experiments. Advantages and limitations to various methods of sample preparation will be described and compared, including starting material, matrix choice, matrix application, and enzyme workflows. Factorial experimental design as well as non-statistical approaches will be presented. Finally, real-world applications to design of tissue and non-tissue imaging projects will be reviewed, along with discussions of rigorous sample preparation reporting strategies.
All meeting workshops will take place in the Elm Ballroom at the SMC Campus Center.
Sunday, July 31st - 3:00pm-5:00pm
Sunday, July 31st - 3:00pm-5:00pm
With the advent of high-throughput technologies, biological experiments have shifted from generating small datasets that focus on single genes or proteins to generating large data sets that document expression profiles on a whole-genome wide basis. Similarly, metabolomicsvtechnologies allow quantification of lipids, glycans and other molecules on a similar scale,leading to the generation of large metabolomics expression profiles. Each of the transcriptomic,proteomic and metabolomics assays offers a different view on the investigated biology that can support findings by the other assays and give additional complementary insights. Integration strategies that map the findings across different assays can help to maximize the insight obtained by the different assays. Integration between metabolomic and transcriptomic or proteomic technologies can be achieved on multiple levels. On the lowest level a researcher can investigate if the transcript omic or proteomic datasets identify enzymes that either directly catalyze reactions of the identified metabolites or of closely related precursors and derivatives.On the second level a researcher can analyze if a set of metabolites maps to a pathway that was identified by the other omic datasets as well. On the highest level a researcher can finally investigate if pathways that were identified for the metabolites are functionally related to pathways identified based on other omic assays. Here, we will discuss the integration of metabolomics with single cell and bulk RNA seq and proteomic datasets. We will investigate theintegration strategies on each of the three different levels. We will also discuss an example where the integration of metabolomics with other omic datasets and prior biological knowledge allows hypothesis generation about function and relevance of a major metabolomics finding.
Workshop 3: An Introduction to SIMS, DESI, and LASEI for Mass Spectrometry Imaging (Part A)
See more about Dr. Gregory L. Fisher via LinkedIn.
DESI and Ambient Ionization (Part B)
Workshop 4: Government Funding Workshop
Tuesday, August 2nd - 1:00pm-3:00pm
This Government Funding Workshop will serve two purposes: (1) provide our attendees with information about how to secure funding from the funding agencies represented and (2) provide a networking space to discuss applications and new research opportunities for imaging mass spectrometry. This workshop will include a panelist Q&A and then a structured networking event.
Workshop Organizer: Colleen Crouch (email@example.com)